Pediatric Hematology-Oncology EHR and AI Medical Billing Software

Pediatric hematology-oncology teams treat childhood cancers and blood disorders over months and years. XEHR keeps protocols, counts, infusions and family details together.

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Chart · Office visit

Lastname, Firstname M. Sample patient · DOB 01/01/1980 · Commercial

Eligible

BP128/82

HR72

BMI26.4

Temp98.6

Progress noteAI Scribe draft

Bruising and fatigue for two weeks; low platelets on labs.

D69.6 Thrombocytopenia, unspecified

ReviewSign note

Diagnosis carried to the claimD69.6

THE HARD PARTS

What makes pediatric hematology-oncology billing hard

Protocols with many cycles

Chemotherapy follows research or standard protocols with dose by body size, and each cycle must be documented.

Infusions and transfusions

Drugs and blood products are billed by units and time, often several on one day.

Chronic blood disorders

Sickle cell disease and hemophilia need lifelong follow-up, factor products and approvals.

WHERE THE WORK HAPPENS

How pediatric hematology-oncology care is delivered and billed

Pediatric hematology-oncology care is centred in children’s hospitals and cancer centers, with day hospitals for infusions and inpatient units for intensive treatment. Visits, chemotherapy and transfusions are billed on the professional claim, often with many drug lines per day. Many children are enrolled in clinical trials, which adds research billing rules.

What payers check on pediatric hematology-oncology claims

Drugs are billed in their defined units, matched to the dose given, with documented waste where required.
Infusion administration is billed by time, so start and stop times must be recorded.
Clinical trial patients need research and routine costs separated on the claim.
Leukemia codes state whether remission has been achieved.
Factor products for bleeding disorders often require prior authorization.

Common pediatric hematology-oncology diagnoses ICD-10-CM

C91.00	Acute lymphoblastic leukemia not having achieved remission
D57.1	Sickle-cell disease without crisis
D66	Hereditary factor VIII deficiency
D69.3	Immune thrombocytopenic purpura
C74.90	Malignant neoplasm of unspecified part of unspecified adrenal gland
Z51.11	Encounter for antineoplastic chemotherapy

Examples only. The provider chooses the code that matches the documented diagnosis, and XEHR checks it against the note and the payer's rules before the claim goes out.

A VISIT ON XEHR

A pediatric hematology-oncology visit, start to payment

1
Counts first

Blood counts are in the chart before the visit and trended.
2
Dose by size

Doses are calculated from current weight and body surface area and documented.
3
Infuse and record

Drugs, blood products, doses and times are recorded as they are given.
4
Bill every line

Visit, drugs and administration go out on one checked claim to the child’s plan.

How XEHR helps

From the pediatric hematology-oncology visit to the payment

Weight and size on every orderCurrent weight and body surface area are shown with each dose.
Every unit recordedDrugs, blood products, doses and times are captured in the infusion record and carried to the claim.
Long-term follow-upVisits, labs and approvals for chronic blood disorders are tracked over years.
AI that waits for youThe AI drafts notes and prepares claims; your providers sign and your billers approve.

Claim · CMS-1500

Sample claimLastname, Firstname M. · DOS 03/04/2026

Scrub passed

Scrubbed
Submitted
Accepted
Paid

Service	Dx	Units	Charge
Office visit	E11.9	1	145.00
A1c test	E11.9	1	28.00
Total			173.00

ERA postedPayment applied, no re-keying

Agentic AI for pediatric hematology-oncology

AI medical billing for pediatric hematology-oncology practices

XEHR is an agentic EHR: AI agents do the administrative work around every pediatric hematology-oncology visit, and your team approves what matters. How agentic AI works

Before the claim leaves

The claim-check agent looks for

Drugs are billed in their defined units, matched to the dose given, with documented waste where required.
Infusion administration is billed by time, so start and stop times must be recorded.
Clinical trial patients need research and routine costs separated on the claim.
Leukemia codes state whether remission has been achieved.

Around the visit

Agents run on their own

Coverage checked before each pediatric hematology-oncology visit
The visit note drafted for the provider to sign
Insurance payments matched and posted
Open claims tracked, denials read and appeals drafted

People decide

Your team stays in charge

Providers sign every note
Billers approve every claim and appeal
Staff submit prior authorizations
Any check can be overridden, with a reason

BUYER'S GUIDE

Questions to ask before you choose a pediatric hematology-oncology EHR

Ask every vendor, including us. The answers show whether a system was built for pediatric hematology-oncology work or only adapted to it.

Ask us on a demo

Are doses calculated from current weight and body surface area?
Does the infusion record capture every drug, product, unit and time?
Can research and routine costs be separated for trial patients?
Are factor product approvals tracked?
Can survivorship care be followed for years?

QUESTIONS

Pediatric Hematology-Oncology practices ask us

Does XEHR support pediatric oncology?

Yes. Protocols, chemotherapy, transfusions and follow-up are documented and billed from one record.

Can XEHR track factor and blood product use?

Yes. Products, doses and dates are recorded for each patient.

Does XEHR handle chemotherapy approvals for children?

Yes. Drugs needing approval are flagged and requests are prepared from the chart.

Can survivors be followed long term?

Yes. Survivorship visits and late-effect screening are tracked in the same record.

Does XEHR support sickle cell day hospitals?

Yes. Day visits, infusions and transfusions are documented and billed.

Can XEHR record transfusion history?

Yes. Products and dates are recorded on the patient record.

Can families see appointments in the portal?

Yes. Appointments are visible in the patient portal.

How much does XEHR cost for a pediatric hematology-oncology practice?

Pricing is published: $189 per provider per month for the Clinical plan, $449 per provider per month for the Practice Suite with billing, or 2.5% of collections for RCM as a Service. Month-to-month, with a BAA on every plan. See pricing.

How long does it take a pediatric hematology-oncology practice to go live?

Small practices are usually live in 2 to 4 weeks, including setup, data migration and training. We agree the plan with you before you sign.

Related specialties

See all specialties

See XEHR set up for pediatric hematology-oncology

A 30-minute walkthrough on a live test environment, with your specialty's templates and billing.

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